Polyclonal Antibodies
Anti-SERPINA9 Polyclonal Antibody for WB, ELISA - Q86WD7
Item Number : CM0020747
Price varies based on specs and customizations
- Application
- WB, ELISA
- Cross Reactivity
- Human
- Protein Weight
- 47kDa
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Core Product Specifications and Parameters
| Parameter | Value |
|---|---|
| Product Name | SERPINA9 Rabbit pAb |
| Remarks/Alias | GCET1; SERPINA11; SERPINA11b; SERPINA9 |
| Species | Human |
| GeneID (human) | 327657 |
| GeneID | 327657 |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 110-210 of human SERPINA9 (NP_783866.2) |
| Source | Rabbit |
| Category | Polyclonal Antibodies |
| Application | WB, ELISA |
| Cross Reactivity | Human |
| SWISS | Q86WD7 |
| Protein Weight | 47kDa |
| Shipping | Ice bag |
Biological Background: SERPINA9 Function and Localization
- SERPINA9, also known as serpin A9, centerin, or germinal center B-cell-expressed transcript 1 (GCET1), is a member of the serpin superfamily of serine protease inhibitors.
- It functions primarily as an inhibitor of trypsin and trypsin-like serine proteases in vitro, and exhibits lower inhibitory activity against plasmin and thrombin.
- The protein is predicted to be secreted, but has also been detected in the cytoplasm and associated with membranes, indicating possible multiple subcellular localizations.
- SERPINA9 is highly expressed in normal germinal center (GC) B-cells and in GC B-cell-derived malignancies, making it a relevant marker for B-cell biology and lymphoma research.
- The protein undergoes alternative splicing, producing multiple isoforms; the canonical form includes a signal peptide and is glycosylated.
- UniProt keywords highlight its roles in protease inhibition, secretion, and potential membrane association, with evidence from proteomics identification.
Experimental Guidance and Technical Tips
- This rabbit polyclonal antibody was raised against an internal region (amino acids 110–210) of human SERPINA9; consider evaluating its reactivity in samples expressing the target, such as germinal center B-cell lines or tissues.
- For Western blot applications, a band around 47 kDa is expected; ensure proper sample preparation and use appropriate loading controls.
- In ELISA, the antibody may be used for detection; pairing with a validated capture antibody could improve assay sensitivity and specificity. Optimize coating and blocking conditions for best results.
CamelBio: Your One-Stop Sourcing Bridge
At CamelBio, we provide diagnostic manufacturers and research laboratories with streamlined access to high-quality IVD raw materials and technical support from concept to clinic. This SERPINA9 rabbit polyclonal antibody is part of our comprehensive portfolio for B-cell biology and serpin-related studies, and we can assist with sourcing validated antibody pairs, bulk ancillary reagents, and custom polyclonal antibody production. Contact us to discuss your specific project needs and procurement requirements.
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