Products Myoglobin (Myo)

rapid test

Myoglobin (Myo) renal impairment rapid test

Item Number : Myo

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Product Overview Table

Attribute Value
Product Name Anti-h Myoglobin
Description Monoclonal mouse antibody, cultured in vitro under conditions free from animal-derived components.
Application LF, IT, FIA
Form/Appearance Liquid, may turn slightly opaque during storage
Concentration 5.0 mg/ml (+/- 10 %)
Isotype IgG2b
Clonality Monoclonal
Epitope N/D
Purity ≥ 95 %
Affinity Constant KA= 1 x 108 1/M
Associated Products Recombinant Myoglobin antigen, Medix Biochemica 610030 and native Myoglobin antigen Lee Biosolutions 431-11.
Buffer 37 mM citrate, 125 mM phosphate, pH 6.0, 0.095 % NaN3 as a preservative
IEF Profile 6.5–7.8
Cross Reactivity Hemoglobin < 0.1 %
Specificity Antibody recognizes human myoglobin

Storage and Transportation Conditions Table

Attribute Value
Storage +2-8°C
Shipping Cold packs
Shelf Life 24 months

Finished Product Performance Indicator Table

Attribute Value
Appearance Product packaging box and aluminum foil packaging bag should be complete and undamaged.
Test strip width The width of the test strip should not exceed ±0.20mm of the nominal value, which is 4.00mm.
Migration Rate The migration rate of the liquid should be no less than 8.0 mm/min.
Minimum Detection Limit (Myo) ≤30 ng/ml
Linear Range (Myo) Within the range of 50 ng/ml ~ 400 ng/ml, the linear correlation coefficient r≥0.990.
Accuracy The relative deviation between the average detected value and the target value of BIORAD cardiac marker control product should be no more than 20%.
Repeatability The repeatability of the kit should be no more than 10%.
Inter-batch Precision The inter-batch difference of the kit should be no more than 15%.
Stability When stored at 4~30℃ in sealed aluminum foil bags, take the product within 1 month of the expiration date for testing, and the test results should meet the requirements of items 2.2~2.7.

Myoglobin (Myo)

Target Introduction:

Myoglobin (Myo) is a protein found in striated muscles, specifically skeletal muscles (attached to bones and tendons) and heart muscles. Its primary function is to deliver oxygen to muscle cells (myocytes), which require a significant amount of oxygen for energy production and constant use.

Clinical Significance and Relationship with Diseases:

A myoglobin test measures the amount of myoglobin in blood or urine to detect muscle damage. When heart or skeletal muscles are injured, myoglobin is released into the bloodstream. Elevated blood myoglobin levels indicate muscle injury, and are typically measured within hours of injury.

Myoglobin is filtered by the kidneys and excreted in urine. Urine myoglobin levels reflect the severity of skeletal muscle damage (rhabdomyolysis). Higher myoglobin levels in urine indicate more severe muscle injury and potential risk of kidney damage, as myoglobin is toxic to the kidneys.

Applications:

Myoglobin is used as a biomarker for:

  • Detection of muscle damage: Elevated levels in blood indicate skeletal or cardiac muscle injury.
  • Assessment of rhabdomyolysis: Myoglobin in urine quantifies the extent of skeletal muscle breakdown.
  • Evaluation of kidney damage risk: High urine myoglobin levels indicate a risk of kidney damage due to myoglobin toxicity.

Technology Transfer

Technology transfer and customization

For research institutions and growing enterprises, especially those in the early stages of development, we offer a comprehensive suite of mature and stable production process technology transfer, along with relevant process documentation. 

Additionally, we can tailor transformation production processes to align with diverse customer requirements and market needs. 

This approach not only expedites the R&D and production process optimization timeline but also significantly reduces time and capital investment for our clients.

Expert lectures

The course will be led by seasoned industry experts, covering a range of topics including immunochromatography knowledge, theoretical explanations of process flows, and hands-on experimental operations. It will systematically address and analyze technical challenges faced by customers in their R&D and production processes, offering practical solutions. 

Additionally, the course will feature demonstrations and practical operation sessions focused on immunochromatography equipment that is of particular interest to participants.

Process

The process unfolds as follows: 

The customer outlines their requirements -> we collaborate to explore feasible solutions -> the customer settles the fee -> based on the provided solution, the customer either attends on-site training or receives remote guidance -> should production issues arise, we dispatch experts to the customer's site to offer on-site guidance and resolve the problems.

Research Outsourcing

We provide a variety of scientific and technical services, including laboratory equipment, experimental materials, data analysis and report writing, etc.

  • ‌Experimental Consumables and Chemical Reagents: We provide a comprehensive range of consumables and chemical reagents required for various experiments to meet the diverse needs of scientific research.
  • ‌Data Analysis: We are responsible for collecting and conducting in-depth analysis of experimental data, generating detailed reports to lay a solid foundation for the presentation of research findings.
  • Technical Support: We offer comprehensive technical support to ensure the smooth progress of experiments, facilitating the successful conduct of research work.
  • ‌Customized Services: We possess the capability to tailor scientific and technological services to meet the specific needs and expectations of our clients, ensuring a high level of alignment and effectiveness in our offerings.
  • ‌One-Stop Services: We provide comprehensive one-stop scientific research services, including equipment rental and experimental material procurement, aiming to deliver a convenient and efficient user experience while streamlining the research process.

Process:

  • Customer Submits Requirements: The customer clearly outlines their research or production needs, laying the foundation for subsequent services.
  • Exploring Feasible Solutions: We engage in in-depth communication with the customer to jointly explore and formulate practical solutions, ensuring the forward-looking and operational nature of the service.
  • Customer Pays Fees: Upon reaching a mutual agreement, the customer settles the relevant fees, providing assurance for the formal initiation of the service.
  • Conducting Experiments or Data Characterization Analysis for the Customer: Based on the agreed-upon plan, we perform experimental operations or data characterization analysis for the customer, ensuring the process is professional and precise.
  • Providing the Customer with a Detailed Experimental Report: Upon completion of the experiments or analysis, we deliver a comprehensive experimental report to the customer, offering robust support for their research or production decisions.

Semi-finished Products (large Packaging)

We can provide semi-finished (bulk packaged) reagents for quick assembly and application in your own country.

Advantages of Semi-Finished Reagents for Local Assembly:

  • Rapid Market Entry: Quick assembly allows for swift deployment and faster market penetration.
  • Compliance: Meets government self-production mandates and local regulatory requirements.
  • Cost Efficiency: Reduces logistics and capital investment costs.
  • Scalability: Flexible production adapts to market demand.
  • Quality Assurance: Ensures consistent quality with local oversight.
  • Competitive Edge: Combines global expertise with local production for a strategic advantage.

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