[KD Validated] Anti-TIMM10 Rabbit Monoclonal Antibody for WB, IHC-P, IF/ICC, ELISA - P62072

Core Product Specifications and Parameters

Biological Background: TIMM10 Function and Localization

• TIMM10, also known as TIM10, is a subunit of the mitochondrial import inner membrane translocase, functioning as a chaperone in the intermembrane space.
• It participates in the import and insertion of multi-pass transmembrane proteins into the mitochondrial inner membrane.
• TIMM10 may also be required for the transfer of beta-barrel precursors from the TOM complex to the SAM complex of the outer membrane.
• The protein acts as a chaperone-like molecule that shields hydrophobic precursors from aggregation and guides them through the mitochondrial intermembrane space.
• TIMM10 is localized to the mitochondrial inner membrane.
• It is ubiquitously expressed, with the highest levels observed in heart, kidney, liver, and skeletal muscle.
• TIMM10 contains disulfide bonds and binds zinc, features essential for its structural stability and function.

Experimental Guidance and Technical Tips

• The immunogen corresponds to the N-terminal region (amino acids 1-90) of human TIMM10, suggesting reactivity with an epitope in this domain.
• The antibody has been tested in WB, IHC-P, IF/ICC, and ELISA; consider optimizing dilution factors for your specific experimental conditions.
• Cross-reactivity with mouse and rat TIMM10 makes this antibody suitable for studies in these model organisms; validate expression in the relevant tissue or cell line.
• For immunohistochemistry or immunofluorescence, include appropriate fixation and antigen retrieval controls to ensure specificity.

CamelBio: Your One-Stop Sourcing Bridge

CamelBio is your dedicated one-stop sourcing partner for IVD raw materials, offering validated antibody pairs, optimized monoclonal/polyclonal antibodies, and bulk ancillary reagents. This anti-TIMM10 rabbit monoclonal antibody supports research into mitochondrial protein import and chaperone biology, reflecting CamelBio’s commitment to supplying high-quality reagents for challenging targets. Whether you need rare-target raw-material sourcing or large-scale production support, CamelBio connects diagnostic manufacturers and researchers with reliable, scalable solutions from concept to clinic.