clia / elisa, rapid test
Hepatitis B virus core antibody (HBcAb) hepatitis b clia / elisa rapid test
Item Number : HBcAb
Price varies based on specs and customizations
- Diseases
- hepatitis b
- Application
- clia / elisa , rapid test
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Product Overview Table
| Feature | Description |
|---|---|
| Product Name | Hepatitis B virus core antibody (HBcAb) / Hep B cAg Antibody |
| Alternate Product Name | HBcAG |
| Classification | Primary Antibody |
| Clonality | Monoclonal Antibody |
| Antibody Isotype | IgG1 kappa light chain |
| Epitope Target | HBcAg |
| Epitope Species | Hepatitis B |
| Product Reactivity/Detection | An epitope corresponding to amino acids 8-20 of denatured core antigen |
| Species Reactivity/Detection | Hep B, Woodchuck hepatitis |
| Applications | WB, IP, IF, FCM, ELISA |
| Vialing Information | Each vial contains 200 µg IgG1 kappa light chain in 1.0 ml of PBS with < 0.1% sodium azide and 0.1% gelatin |
| Description | Mouse monoclonal IgG1 kappa light chain antibody that can detect Hep B cAg in Hepatitis B and Woodchuck hepatitis. Available in unconjugated and conjugated forms (Agarose, HRP, PE, FITC, and Alexa Fluor® conjugates). |
| Target | HBcAb (also known as anti-HBc) |
Storage and Transportation Conditions Table
| Condition | Description |
|---|---|
| Storage | 2~8℃, protected from light, unopened. |
Finished Product Performance Indicator Table
| Indicator | Requirements |
|---|---|
| Appearance | Liquid components should be clear and transparent. Kit components should be complete and intact, without leakage. Packaging labels should be clear and without damage. |
| Fill Volume | Each component should not be less than the labeled value. |
| Positive Reference Compliance Rate | When testing 15 HBcAb national positive reference materials (or enterprise positive reference materials standardized by national positive reference materials), the positive reference compliance rate (+/+) shall not be less than 14/15. |
| Negative Reference Compliance Rate | When testing 15 HBcAb national negative reference materials (or enterprise negative reference materials standardized by national negative reference materials), the negative reference compliance rate (-/-) shall be 15/15. |
| Minimum Detection Limit | When measuring with HBcAb national minimum detection limit reference material (or enterprise minimum detection limit reference material standardized by national minimum detection limit reference material), the reactivity of the 1# reference material detection result shall not be less than 1:128, the reactivity of the 2# reference material detection result shall not be less than 1:128, and the reactivity of the 3# reference material detection result shall not be less than 1:256. |
| Repeatability | When testing with HBcAb national precision reference material (or enterprise precision reference material standardized by national precision reference material), repeatedly measure 10 times, and its coefficient of variation (CV) should be no more than 10%. |
| Batch-to-Batch Difference | When testing three batches of kits with HBcAb national precision reference material (or enterprise precision reference material standardized by national precision reference material), the inter-batch coefficient of variation (CV) should be no more than 15%. |
| Calibrator Accuracy | The relative deviation of the calibrator should be no more than ±10%. |
| Calibrator Uniformity | The uniformity of the calibrator should be no more than 10%. |
| Stability | When the kit is stored at 2~8℃ protected from light in an unopened state, take the product within 6 months after the expiration date and test according to 2.1~2.5, 2.7 and 2.8, and the results should meet the requirements of relevant items. |
Hepatitis B virus core antibody (HBcAb)
Introduction:
Hepatitis B virus core antibody (HBcAb), also known as anti-HBc, is an antibody detectable in the serum of most individuals after HBV infection. It serves as a sensitive serological marker and an early indicator of acute hepatitis B infection. HBcAb can persist in the serum for a long time, sometimes at high titers. It is not a protective antibody.
HBcAb can be classified into three types: anti-HBc IgM, anti-cIgA, and anti-HBc IgG. These types appear and disappear sequentially during HBV infection, with only IgG persisting long-term.
Hep B cAg antibody (10E11) is a mouse monoclonal IgG1 kappa light chain antibody that can detect Hep B cAg in hepatitis B and woodchuck hepatitis through Western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), flow cytometry (FCM), and enzyme-linked immunosorbent assay (ELISA). Anti-Hep B cAg antibody (10E11) recognizes an epitope corresponding to amino acids 8-20 of denatured core antigen of Hepatitis B virus. Core antigen plays a crucial role in viral capsid assembly, encapsulating the viral genome, and ensuring stability during replication. This structural integrity is critical for viral infection of host cells and evasion of immune responses, making the core antigen a key target for diagnostic and therapeutic strategies. Hep B cAg monoclonal antibody (10E11) is available in unconjugated and conjugated forms including Agarose, Horseradish Peroxidase (HRP), Phycoerythrin (PE), Fluorescein Isothiocyanate (FITC) and multiple Alexa Fluor® conjugates to accommodate diverse experimental needs. Hepatitis B virus is a member of the hepadnavirus family and can lead to severe liver inflammation, jaundice, and potentially fatal consequences, highlighting the importance of accurate antigen detection and monitoring in clinical settings.
Technology Transfer
Technology transfer and customization
For research institutions and growing enterprises, especially those in the early stages of development, we offer a comprehensive suite of mature and stable production process technology transfer, along with relevant process documentation.
Additionally, we can tailor transformation production processes to align with diverse customer requirements and market needs.
This approach not only expedites the R&D and production process optimization timeline but also significantly reduces time and capital investment for our clients.
Expert lectures
The course will be led by seasoned industry experts, covering a range of topics including immunochromatography knowledge, theoretical explanations of process flows, and hands-on experimental operations. It will systematically address and analyze technical challenges faced by customers in their R&D and production processes, offering practical solutions.
Additionally, the course will feature demonstrations and practical operation sessions focused on immunochromatography equipment that is of particular interest to participants.
Process
The process unfolds as follows:
The customer outlines their requirements -> we collaborate to explore feasible solutions -> the customer settles the fee -> based on the provided solution, the customer either attends on-site training or receives remote guidance -> should production issues arise, we dispatch experts to the customer's site to offer on-site guidance and resolve the problems.
Research Outsourcing
We provide a variety of scientific and technical services, including laboratory equipment, experimental materials, data analysis and report writing, etc.
- Experimental Consumables and Chemical Reagents: We provide a comprehensive range of consumables and chemical reagents required for various experiments to meet the diverse needs of scientific research.
- Data Analysis: We are responsible for collecting and conducting in-depth analysis of experimental data, generating detailed reports to lay a solid foundation for the presentation of research findings.
- Technical Support: We offer comprehensive technical support to ensure the smooth progress of experiments, facilitating the successful conduct of research work.
- Customized Services: We possess the capability to tailor scientific and technological services to meet the specific needs and expectations of our clients, ensuring a high level of alignment and effectiveness in our offerings.
- One-Stop Services: We provide comprehensive one-stop scientific research services, including equipment rental and experimental material procurement, aiming to deliver a convenient and efficient user experience while streamlining the research process.
Process:
- Customer Submits Requirements: The customer clearly outlines their research or production needs, laying the foundation for subsequent services.
- Exploring Feasible Solutions: We engage in in-depth communication with the customer to jointly explore and formulate practical solutions, ensuring the forward-looking and operational nature of the service.
- Customer Pays Fees: Upon reaching a mutual agreement, the customer settles the relevant fees, providing assurance for the formal initiation of the service.
- Conducting Experiments or Data Characterization Analysis for the Customer: Based on the agreed-upon plan, we perform experimental operations or data characterization analysis for the customer, ensuring the process is professional and precise.
- Providing the Customer with a Detailed Experimental Report: Upon completion of the experiments or analysis, we deliver a comprehensive experimental report to the customer, offering robust support for their research or production decisions.
Semi-finished Products (large Packaging)
We can provide semi-finished (bulk packaged) reagents for quick assembly and application in your own country.
Advantages of Semi-Finished Reagents for Local Assembly:
- Rapid Market Entry: Quick assembly allows for swift deployment and faster market penetration.
- Compliance: Meets government self-production mandates and local regulatory requirements.
- Cost Efficiency: Reduces logistics and capital investment costs.
- Scalability: Flexible production adapts to market demand.
- Quality Assurance: Ensures consistent quality with local oversight.
- Competitive Edge: Combines global expertise with local production for a strategic advantage.
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