Anti-TES Rabbit Polyclonal Antibody for WB, IHC-P, ELISA - Q9UGI8

Core Product Specifications and Parameters

Biological Background: Testin Function and Localization

• Testin is a scaffold protein encoded by the TES gene, also known as TESS.
• It plays a role in cell adhesion, cell spreading, and the reorganization of the actin cytoskeleton.
• Testin is involved in the regulation of cell proliferation and may act as a tumor suppressor, inhibiting tumor cell growth.
• The protein localizes to the cytoplasm and is enriched at cell junctions and focal adhesions.
• Testin is ubiquitously expressed across tissues.
• Key structural features include LIM domains, zinc-binding motifs, and repeat regions; the protein is subject to alternative splicing.
• Additional annotations: 3D-structure, proteomics identification, reference proteome.

Experimental Guidance and Technical Tips

• The immunogen corresponds to amino acids 1–260 of human TES, encompassing the N-terminal region; consider this when designing detection or blocking strategies.
• For Western blot (WB), a band around 48 kDa is expected; optimize antibody dilution based on sample lysate and detection system.
• In immunohistochemistry (paraffin-embedded, IHC-P), validate with appropriate antigen retrieval and tissue-specific controls.
• For ELISA, test coating antigen conditions and confirm specificity using recombinant protein or known positive controls.
• Cross-reactivity with human and rat suggests utility in both species; verify reactivity in your specific model system.
• As TES is involved in cell adhesion and tumor suppression, this antibody may support functional studies; however, performance should be confirmed in relevant assays.

CamelBio: Your One-Stop Sourcing Bridge

CamelBio provides diagnostic manufacturers, laboratories, and research institutes with one-stop access to IVD raw materials, technical services, and consulting—from concept to clinic. The TES rabbit pAb targets a scaffold protein involved in cell adhesion and tumor suppression, making it relevant for oncology and cell biology research. We support your projects with validated antibody pairs, optimized monoclonal and polyclonal antibodies, bulk ancillary reagents, and custom sourcing for rare targets.