ZNF544 Rabbit pAb - Q6NX49

Core Product Specifications and Parameters

Biological Background: ZNF544 Function and Localization

• ZNF544 is a zinc finger protein encoded by the ZNF544 gene in humans (UniProt Q6NX49).
• The protein is predicted to function as a DNA-binding transcription factor, potentially involved in transcriptional regulation.
• Subcellular localization is nuclear, consistent with its role in gene regulation.
• It contains multiple zinc finger domains of the C2H2 type, enabling sequence-specific DNA binding.
• Post-translational modifications include ubiquitination, as indicated by the keyword 'Isopeptide bond' and 'Ubl conjugation'.
• ZNF544 has been identified in proteomics analyses and is part of the reference human proteome.

Experimental Guidance and Technical Tips

• The immunogen corresponds to the N-terminal region (amino acids 1-230) of human ZNF544. This design may enable recognition of the full-length protein.
• For Western blotting, a band at approximately 82 kDa is expected. Validate detection in relevant sample lysates.
• The antibody has reported cross-reactivity with mouse, but experimental validation is recommended for each application.

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