ZNF384 Rabbit pAb for WB, IHC-P, ELISA - Q8TF68

Core Product Specifications and Parameters

Biological Background: ZNF384 Function and Localization

• ZNF384 is a zinc finger transcription factor that binds the consensus DNA sequence [GC]AAAAA, regulating genes such as MMP1, MMP3, MMP7, and COL1A1 (By similarity).
• It is also known as CIZ, NMP4, CAGH1, ERDA2, TNRC1, and CAGH1A, reflecting its identification in various contexts including CAG repeat expansion and nuclear matrix association.
• The protein localizes to the nucleus, consistent with its role in transcriptional regulation.
• ZNF384 belongs to the krueppel C2H2-type zinc-finger protein family, characterized by conserved zinc-binding domains that mediate DNA interaction.
• According to UniProt, the protein undergoes alternative splicing and is subject to phosphorylation, indicating potential regulatory mechanisms.
• It is predicted to contain metal-binding zinc-finger motifs and repeat regions, common features of transcription factors.

Experimental Guidance and Technical Tips

• The immunogen for this antibody is a recombinant fusion protein corresponding to amino acids 1-80 of human ZNF384 (NP_001129206.1). This N-terminal region may confer specificity for certain isoforms or enable detection across species.
• Recommended applications include Western blot (WB), immunohistochemistry (IHC-P), and ELISA. For WB, the predicted protein weight is approximately 63kDa; consider using appropriate blocking and controls.
• Given cross-reactivity with mouse and rat, consider validating the antibody in the relevant sample systems and including tissue-specific or cell-based controls.

CamelBio: Your One-Stop Sourcing Bridge

CamelBio provides diagnostic manufacturers, laboratories, and research institutes with one-stop access to IVD raw materials like this ZNF384 rabbit polyclonal antibody. As a transcription factor implicated in development and disease, ZNF384 represents a key target in oncology and epigenetics research. Our supply capabilities include validated antibody pairs, optimized monoclonal and polyclonal antibodies, bulk ancillary reagents, and sourcing support for rare-target raw materials.