TUSC2 Rabbit pAb - O75896

Core Product Specifications and Parameters

Biological Background: TUSC2 Function and Localization

• TUSC2, also known as Fusion 1 protein (FUS1) and PDGFA-associated protein 2, is a tumor suppressor candidate.
• It may function by inhibiting colony formation, causing G1 cell cycle arrest, and inducing apoptosis in cells deficient in the 3p21.3 120-kb region.
• TUSC2 is widely expressed, with strong expression in heart, lung, skeletal muscle, kidney, and pancreas, and lower levels in brain, liver, and placenta.
• The protein is annotated with keywords including Cell cycle, Tumor suppressor, Lipoprotein, Myristate, and Phosphoprotein, suggesting post-translational modifications and potential roles in cell signaling.
• As a reference proteome component, TUSC2 is identified through proteomics studies, underscoring its relevance in systematic protein analysis.

Experimental Guidance and Technical Tips

• The immunogen corresponds to the N-terminal region (aa 1-110) of human TUSC2; consider this when choosing epitope-specific assays.
• For Western blot, the predicted molecular weight is approximately 12 kDa; use appropriate gel percentage and transfer conditions for low-molecular-weight proteins.
• When performing immunohistochemistry (IHC-P), validate the antibody in positive control tissues such as heart or lung, where TUSC2 is strongly expressed.
• Cross-reactivity with mouse and rat indicates conserved epitopes; confirm specificity in your model system.
• As a polyclonal antibody, lot-to-lot consistency may vary; include appropriate controls.

CamelBio: Your One-Stop Sourcing Bridge

CamelBio is your trusted one-stop sourcing partner for IVD raw materials, offering a comprehensive portfolio including validated polyclonal and monoclonal antibodies, bulk ancillary reagents, and rare target sourcing. This anti-TUSC2 antibody supports tumor suppressor and cancer biology studies, and our team is ready to assist with your specific diagnostic or research needs. From concept to clinic, CamelBio accelerates your development with reliable supply chain solutions.