TP53I11 Rabbit pAb - O14683

Core Product Specifications and Parameters

Biological Background: TP53I11 Function and Localization

• TP53I11, also known as PIG11 (p53-induced gene 11 protein), is a p53-inducible protein encoded by the TP53I11 gene.
• It is a transmembrane protein predicted to contain a transmembrane helix, as indicated by its membrane subcellular localization.
• The protein has a molecular weight of approximately 21 kDa.
• TP53I11 is classified as a phosphoprotein based on proteomics identification, suggesting post-translational regulation by phosphorylation.
• As a p53 target gene, it is likely involved in p53-mediated cellular responses, though its exact function remains to be fully elucidated.
• The protein has been cataloged in reference proteome datasets and has been identified in proteomics studies.

Experimental Guidance and Technical Tips

• For Western blot, a 12–15% SDS-PAGE gel is recommended to resolve the ~21 kDa band; validate in the relevant sample system.
• Antigen retrieval optimization may be necessary for IHC-P; consider testing different conditions on control tissues.
• This polyclonal antibody is suitable for ELISA; perform titration experiments to determine the optimal working concentration.
• Given the polyclonal nature, slight variations between batches may occur; always include appropriate controls.

CamelBio: Your One-Stop Sourcing Bridge

CamelBio serves as a comprehensive sourcing partner for IVD raw materials, offering validated antibody pairs, optimized monoclonal and polyclonal antibodies, and bulk ancillary reagents to support research in p53 signaling and apoptosis. Whether you need pre-validated reagents or assistance in sourcing rare targets like TP53I11, CamelBio streamlines your procurement from concept to clinic.