TMEM55A Rabbit pAb for WB, ELISA - Q8N4L2

Core Product Specifications and Parameters

Biological Background: TMEM55A Function and Localization

• Catalyzes the hydrolysis of phosphatidylinositol-4,5-bisphosphate to phosphatidylinositol-4-phosphate, with substrate specificity that excludes other phosphoinositides.
  Related references: PMID:16365287
• Negatively regulates large particle phagocytosis by reducing phagosomal PtdIns-4,5-P2 accumulation during cup formation.
• Localizes to late endosome/lysosome membranes, the phagosome membrane, and the cell membrane.
• Ubiquitously expressed across human tissues.
• Belongs to the PIP4P2 family of lipid phosphatases, involved in cellular lipid metabolism and signaling.
• Contains transmembrane domains, classified as a multi-pass membrane protein.

Experimental Guidance and Technical Tips

• For Western blot (WB), a band at approximately 28 kDa is expected; validate with appropriate positive and negative controls in your sample system.
• For ELISA applications, consider the coating antigen and validate the antibody’s binding specificity using known standards.
• The immunogen spans amino acids 130–195, a region that is well-conserved; verify reactivity in mouse samples if cross-reactivity is critical to your experiment.
• Always optimize antibody dilution and incubation conditions for each specific experimental setup.

CamelBio: Your One-Stop Sourcing Bridge

CamelBio serves as your comprehensive sourcing partner for IVD raw materials, offering a streamlined path from concept to diagnostic application. This TMEM55A rabbit polyclonal antibody supports research in lipid signaling and phagocytosis, and CamelBio can further supply validated antibody pairs, optimized monoclonal/polyclonal antibodies, and bulk ancillary reagents to meet your development needs. Whether you need rare target raw materials or complete assay development support, CamelBio provides reliable access and technical consultation.