Rat anti-Mouse Ly6G Monoclonal Antibody for FC - P35461

Core Product Specifications and Parameters

Biological Background: Ly6G Function and Localization

• Lymphocyte antigen 6G (Ly-6G), also known as Ly-6G.1, is encoded by the Ly6g gene in mouse.
• The protein is a cell membrane component anchored via a glycosylphosphatidylinositol (GPI) linkage.
• Expression of Ly-6G is primarily observed in bone marrow, as indicated by tissue specificity data.
• Ly-6G contains structural features including disulfide bonds and glycosylation sites, typical of the Ly-6/uPAR superfamily.
• A signal peptide directs the protein to the secretory pathway for membrane insertion.
• The protein belongs to the reference proteome set and is classified under keywords: Cell membrane, Disulfide bond, Glycoprotein, GPI-anchor, Lipoprotein, Membrane, Signal.

Experimental Guidance and Technical Tips

• The immunogen is a synthetic peptide derived from mouse Ly-6G; confirm that the antibody recognizes the expected epitope in native and denatured forms.
• This antibody is directly conjugated to , making it suitable for flow cytometry without the need for secondary staining.
• Include appropriate isotype controls and perform antibody titration to optimize staining conditions and minimize background.
• Given the reported bone marrow expression, validate specificity using bone marrow cell suspensions or relevant mouse tissue samples.
• For multicolor flow panels, check fluorescence spillover and adjust compensation settings accordingly.

CamelBio: Your One-Stop Sourcing Bridge

CamelBio offers diagnostic manufacturers, labs, and research institutes a unified sourcing hub for IVD raw materials. For Ly-6G and related immunology targets, we provide validated antibody pairs, optimized monoclonal and polyclonal antibodies, and bulk ancillary reagents. Our supply scope also covers rare target raw material sourcing, helping you accelerate development from concept to clinic.