Rabbit anti-Pig CD8a Monoclonal Antibody for FC - A0A287A9Y5

Core Product Specifications and Parameters

Biological Background: T-cell surface glycoprotein CD8 alpha chain Function and Localization

• The protein is identified as T-cell surface glycoprotein CD8 alpha chain (UniProt: A0A287A9Y5), a component of the CD8 coreceptor complex essential for adaptive immunity.
• It localizes to the cell membrane.
• The protein contains an immunoglobulin domain, characteristic of the immunoglobulin superfamily.
• Post-translational modifications include glycosylation and lipidation (palmitate), and it features a disulfide bond.
• The molecule spans the membrane via a transmembrane helix and includes a signal peptide for membrane targeting.
• Its molecular weight is approximately 26 kDa (calculated from sequence: 26474 Da; observed 26 kDa).

Experimental Guidance and Technical Tips

• The antibody is conjugated to , a far-red fluorescent dye suitable for flow cytometry; consider optimizing titers for specific cell populations.
• Since the immunogen spans the extracellular region, the antibody is expected to recognize cell surface CD8a; confirm expression on relevant T-cell subsets.
• Validate staining specificity using appropriate isotype controls and knockout/knockdown models if available.
• For multicolor panels, ensure compatibility with other fluorophores in the far-red channel.

CamelBio: Your One-Stop Sourcing Bridge

CamelBio provides a comprehensive IVD raw-material sourcing solution, connecting diagnostic manufacturers and researchers with validated antibody pairs, optimized monoclonal/polyclonal antibodies, bulk ancillary reagents, and rare target procurement. This anti-Pig CD8a monoclonal antibody supports swine immunological studies, and as your supply partner, CamelBio ensures efficient access to reliable reagents for your research and development needs.