Rabbit anti-Pig CD138 Monoclonal Antibody for FC - K7GNF5

Core Product Specifications and Parameters

Biological Background: Syndecan Function and Localization

• Syndecan (CD138) is a transmembrane proteoglycan that contains both heparan sulfate and chondroitin sulfate chains, serving as a key link between the cytoskeleton and the interstitial matrix.
• It regulates exosome biogenesis by interacting with SDCBP (syntenin) and PDCD6IP (ALIX).
• Syndecan can induce its own expression in dental mesenchymal cells and neighboring epithelial cells via an MSX1-mediated pathway, playing a role in developmental signaling.
• Subcellular localization includes the plasma membrane, secreted forms, and incorporation into extracellular exosomes.
• Post-translational modifications include glycosylation (heparan sulfate and chondroitin sulfate attachment), phosphorylation, and proteolytic shedding.
• Keywords associated with this protein: Glycoprotein, Heparan sulfate, Membrane, Phosphoprotein, Proteoglycan, Secreted, Signal, Transmembrane.

Experimental Guidance and Technical Tips

• This antibody is directly conjugated to , making it ready-to-use for flow cytometry without the need for a secondary antibody.
• Consider titrating the antibody to determine the optimal staining concentration for your specific cell type and experimental conditions.
• Since the immunogen corresponds to the extracellular domain (aa 23-250), the antibody is expected to recognize surface-expressed CD138; permeabilization is not required for surface staining.
• Validate performance in appropriate pig-derived cell lines or primary cells known to express CD138, and include proper isotype controls and blocking steps.

CamelBio: Your One-Stop Sourcing Bridge

CamelBio provides comprehensive access to IVD raw materials, including validated antibody pairs, optimized monoclonal and polyclonal antibodies, and bulk ancillary reagents for diagnostic development. For researchers focused on cell surface proteoglycans, exosome biology, or dental mesenchymal signaling, this anti-pig CD138 antibody supports robust flow cytometry detection. Our sourcing capabilities also extend to rare target raw materials, ensuring a reliable supply chain from concept to clinic.