Rabbit anti-Mouse CD201/EPCR Monoclonal Antibody for Flow Cytometry - Q64695

Core Product Specifications and Parameters

Biological Background: CD201/EPCR Function and Localization

• EPCR, encoded by the PROCR gene, is a transmembrane receptor with aliases Ccca, Epcr, and Ccd41. It belongs to the coagulation/hemostasis receptor family and contains a single transmembrane helix.
• It binds activated protein C and enhances protein C activation by the thrombin-thrombomodulin complex, thereby playing a central role in the protein C anticoagulant pathway and control of blood coagulation.
• EPCR is predominantly expressed on the membrane of endothelial cells, consistent with its role in vascular hemostasis.
• The protein is a glycoprotein with a disulfide bond and an N-terminal signal peptide, supporting proper cell surface targeting and structural stability.
• Key associated biological processes include blood coagulation, hemostasis, and cellular response to activated protein C.

Experimental Guidance and Technical Tips

• The immunogen covers the extracellular region (amino acids 18–210) of mouse EPCR, making the antibody likely to recognize the native surface receptor for flow cytometry.
• This antibody is supplied as a pre-conjugated derivative, allowing direct detection in FC without secondary reagents.
• For optimal staining, consider titrating the antibody on mouse endothelial cells or EPCR-expressing cells as a positive control.
• Although validated for flow cytometry, cross-reactivity with other species has not been reported; restrict use to mouse samples unless independently verified.

CamelBio: Your One-Stop Sourcing Bridge

CamelBio is your one-stop sourcing partner for IVD raw materials, offering validated antibodies, reagents, and integrated technical support to accelerate diagnostic development. This anti-mouse CD201/EPCR monoclonal antibody, conjugated to , exemplifies our commitment to providing high-quality tools for coagulation research and endothelial cell studies. Whether you need custom antibody development, bulk supply, or technical consultation, CamelBio bridges the gap from concept to clinical application.