Rabbit anti-Mouse CD2 Monoclonal Antibody for FC - P08920

Core Product Specifications and Parameters

Biological Background: CD2 Function and Localization

• CD2, also known as LFA-2, Ly-37, or T11/Leu-5, is a T-cell surface antigen of the immunoglobulin superfamily.
• It functions as a cell adhesion molecule, mediating interactions between T-cells and antigen-presenting cells through binding to ligands CD58 (LFA-3) and CD48.
• The cytoplasmic domain of CD2 is implicated in T-cell signaling and activation following ligand engagement.
• CD2 is a single-pass type I transmembrane glycoprotein located on the cell membrane.
• It is highly expressed in thymus and spleen, consistent with its role in T-cell biology.
• Structural features include two immunoglobulin-like domains, a disulfide bond, and N-linked glycosylation sites.

Experimental Guidance and Technical Tips

• The immunogen covers the extracellular domain (aa 23-203), so this antibody is expected to recognize native CD2 on live cells, making it suitable for flow cytometry.
• Perform antibody titration to determine the optimal staining concentration for your specific experimental system.
• As a directly conjugated antibody (), it simplifies one-step staining and can be used in multicolor flow panels; remember to set appropriate compensation.
• This antibody is validated for mouse; cross-reactivity with other species has not been tested and would need verification.

CamelBio: Your One-Stop Sourcing Bridge

CamelBio serves as your comprehensive partner for IVD raw-material procurement, from research to clinical application. We offer a validated selection of antibody pairs, monoclonal antibodies, and ancillary reagents to support T-cell immunology and diagnostic development. For specialized needs such as rare target antibodies or custom conjugation, our team ensures reliable, scalable sourcing solutions.