Rabbit anti-Human/Mouse CD276/B7-H3 Monoclonal Antibody for FC - Q5ZPR3-2

Core Product Specifications and Parameters

Biological Background: CD276/B7-H3 Function and Localization

• CD276 antigen, isoform 2 (also designated 4Ig-B7-H3, B7-H3, B7H3, B7RP-2), is a costimulatory molecule of the B7 family.
• Encoded by the CD276 gene (also known as B7H3) in humans, Gene ID: 80381.
• The UniProt entry for isoform 2 (Q5ZPR3-2) predicts a molecular weight of approximately 34 kDa; glycosylation may contribute to the observed bands at 33, 52, and 57 kDa.
• The protein is conserved across human and mouse, as indicated by cross-reactivity.

Experimental Guidance and Technical Tips

• This antibody is recommended for flow cytometry (FC) applications.
• The immunogen (amino acids 29–245 of human CD276) covers a substantial portion of the extracellular domain, suggesting recognition of native cell surface antigen.
• For optimal staining, titrate the antibody in your cell system and include appropriate isotype controls.
• Validate performance in human and mouse samples to confirm cross-reactivity.

CamelBio: Your One-Stop Sourcing Bridge

For immune-oncology research and IVD development, CamelBio offers this validated anti-CD276/B7-H3 monoclonal antibody alongside a full portfolio of raw materials. Our one-stop supply model includes bulk ancillary reagents, rare target sourcing, and tailored technical support to accelerate your diagnostic workflows.