Rabbit anti-Human CD96/TACTILE Monoclonal Antibody for Flow Cytometry - P40200

Core Product Specifications and Parameters

Biological Background: T-cell surface protein tactile Function and Localization

• CD96 (T-cell surface protein tactile) is a member of the immunoglobulin superfamily and functions as a cell adhesion molecule.
• It mediates adhesive interactions of activated T and NK cells during late immune responses by binding to PVR (CD155) on target cells.
• CD96 may facilitate lymphocyte engagement with diseased cells within inflamed tissues after extravasation.
• The protein is a transmembrane glycoprotein with immunoglobulin-like domains, disulfide bonds, and undergoes alternative splicing.
• Expression is primarily on T-cell lines, clones, and some transformed T-cells, with very low levels on activated B-cells.
• Mutations in CD96 are associated with craniosynostosis and other disease variants.

Experimental Guidance and Technical Tips

• The immunogen corresponds to the extracellular region (aa 25-519); ensure native conformation for optimal recognition of cell surface CD96.
• For flow cytometry, titrate the antibody to determine the optimal concentration for your specific cell type; use appropriate isotype controls.
• Since the antibody is rabbit monoclonal, cross-reactivity is restricted to human CD96; validate expression in your target cells.
• The conjugate is suitable for flow cytometry; use appropriate filter sets and compensation controls.

CamelBio: Your One-Stop Sourcing Bridge

CamelBio provides one-stop sourcing for IVD raw materials, including this anti-CD96 antibody for immune cell adhesion and NK/T-cell research. We supply validated antibody pairs, optimized monoclonal/polyclonal antibodies, bulk reagents, and rare target sourcing to support diagnostic development from concept to clinic. For research into CD96-mediated adhesion, our offerings streamline your path to reliable assays.