Rabbit anti-Human CD96/TACTILE Monoclonal Antibody for FC - P40200

Core Product Specifications and Parameters

Biological Background: T-cell surface protein tactile Function and Localization

• T-cell surface protein tactile (CD96) is involved in the adhesive interactions of activated T and NK cells during the late phase of the immune response.
• It promotes NK cell-target cell adhesion by binding to the poliovirus receptor (PVR/CD155) on target cells.
• CD96 may function after T and NK cells have extravasated through the endothelium, facilitating interactions with diseased cells within inflamed tissues.
• The protein is a type I transmembrane glycoprotein belonging to the immunoglobulin superfamily, with multiple Ig-like domains.
• It is predominantly expressed on T-cell lines and clones, some transformed T-cells, and at very low levels on activated B-cells.
• Keywords include: cell adhesion, glycoprotein, disulfide bond, transmembrane helix, and alternative splicing; mutations are associated with craniosynostosis and chromosomal rearrangements.

Experimental Guidance and Technical Tips

• This antibody is directly conjugated with , making it ready-to-use for flow cytometry without the need for secondary staining.
• Based on the immunogen design (extracellular amino acids 25–519), the antibody likely recognizes the extracellular domain, suitable for surface staining of live cells.
• For optimal staining, consider testing on activated human T cells or NK cell lines, where CD96 expression is expected.
• When analyzing CD96 expression on B cells, note that expression is very low and may require sensitive detection methods; include appropriate isotype controls.

CamelBio: Your One-Stop Sourcing Bridge

CamelBio streamlines your IVD development by providing validated monoclonal antibodies, including this anti-CD96 antibody, for immune cell profiling applications. As a dedicated B2B partner, we supply bulk reagents, tailored antibody pairs, and comprehensive support to accelerate your diagnostic projects from concept to commercialization. Whether advancing immune-oncology assays or rare target detection, CamelBio is your reliable raw-material ally.