Rabbit anti-Human CD9 Monoclonal Antibody for FC - P21926

Core Product Specifications and Parameters

Biological Background: CD9 Function and Localization

• CD9 is a member of the tetraspanin superfamily, also known as TSPAN29, MRP-1, and p24, and is a 25 kDa integral membrane glycoprotein.
• It plays a critical role in cell adhesion and cell motility, influencing tumor metastasis. Related references: PMID:7511626 PMID:8478605
• CD9 is essential for sperm-egg fusion, likely by organizing membrane multiprotein complexes (By similarity).
• It regulates platelet activation and aggregation. Related references: PMID:18541721
• In macrophages, CD9 associates with CD81 and integrins to prevent macrophage fusion into multinucleated giant cells. Related references: PMID:12796480
• CD9 is predominantly localized on the cell membrane and is also secreted in extracellular exosomes.
• Detected in platelets and expressed by hematopoietic and epithelial cells. Related references: PMID:19640571

Experimental Guidance and Technical Tips

• The immunogen corresponds to the extracellular domain (amino acids 1-228), making this conjugated antibody suitable for direct flow cytometric detection of surface CD9.
• Consider titrating the antibody to determine the optimal concentration for your specific cell type and experimental conditions.
• CD9 is also present on exosomes; ensure appropriate gating strategies to distinguish cells from debris in flow cytometry.
• Validate the antibody performance in your sample system and include appropriate isotype controls.

CamelBio: Your One-Stop Sourcing Bridge

CamelBio provides diagnostic manufacturers and research laboratories with one-stop access to IVD raw materials, technical services, and consulting. This anti-CD9 antibody supports immunology, oncology, and exosome research applications. We offer validated antibody pairs, optimized monoclonal/polyclonal antibodies, and bulk ancillary reagents, along with custom sourcing for rare targets—helping you bridge from concept to clinic efficiently.