Rabbit anti-Human CD45RA Monoclonal Antibody for Flow Cytometry - P08575-8

Core Product Specifications and Parameters

Biological Background: CD45RA Function and Localization

• CD45RA is isoform 6 of Receptor-type tyrosine-protein phosphatase C (PTPRC), encoded by the human PTPRC (CD45) gene.
• It is commonly referred to as Leukocyte common antigen (L-CA) or T200, reflecting its abundant leukocyte expression.
• The protein has a calculated molecular weight of approximately 138 kDa.
• As a receptor-type tyrosine phosphatase, it is recognized as a key regulator of cellular signaling in immune cells.
• It is expressed in Homo sapiens (Human).

Experimental Guidance and Technical Tips

• The immunogen encompasses amino acids 26–482 of human CD45RA (P08575-8), covering the extracellular region, making it suitable for detecting cell surface CD45RA by flow cytometry.
• This antibody is directly conjugated to , so no secondary labeling is needed; use appropriate isotype controls and Fc block to reduce nonspecific binding.
• Validate performance in your human leukocyte sample system; variables such as cell viability, fixation, and permeabilization may influence epitope accessibility.
• Titrate the antibody to determine the optimal concentration for your specific flow cytometry panel and instrument.

CamelBio: Your One-Stop Sourcing Bridge

CamelBio partners with diagnostic manufacturers and research laboratories to supply a comprehensive range of IVD raw materials, including validated antibodies like this CD45RA monoclonal antibody. Our portfolio supports immunophenotyping and immune monitoring applications, offering bulk quantities and custom sourcing for rare targets. With expertise spanning the IVD development pipeline, we help accelerate your assay development from concept to clinic.