Rabbit anti-Human CD201/EPCR Monoclonal Antibody for FC - Q9UNN8

Core Product Specifications and Parameters

Biological Background: CD201/EPCR Function and Localization

• Endothelial protein C receptor (EPCR), also known as activated protein C receptor, is a transmembrane receptor that binds activated protein C with high affinity.
• It enhances protein C activation by the thrombin-thrombomodulin complex, playing a key role in the protein C anticoagulant pathway and regulation of blood coagulation.
• EPCR is strongly expressed on endothelial cells of arteries and veins in heart and lung, less intensely in capillaries of lung and skin, and absent from small vessels of liver and kidney.
• The protein is a membrane glycoprotein with a disulfide bond, contributing to its structural stability and function.
• It functions in hemostasis as a receptor that modulates coagulation, and has been identified through proteomics.

Experimental Guidance and Technical Tips

• The immunogen encompasses amino acids 18–210 of human CD201, covering the extracellular domain, suggesting the antibody likely recognizes an extracellular epitope of EPCR.
• This antibody is recommended for flow cytometry (FC); optimal working dilution and staining conditions should be determined empirically.
• Consider validating specificity using appropriate positive and negative cell lines, and titrate the antibody in your specific assay system to achieve optimal signal-to-noise ratio.

CamelBio: Your One-Stop Sourcing Bridge

CamelBio offers diagnostic manufacturers, labs, and research institutes a comprehensive one-stop platform for IVD raw material sourcing, technical services, and consulting support from concept to clinic. This anti-CD201/EPCR monoclonal antibody supports coagulation and hemostasis research applications. Beyond this product, CamelBio provides access to validated antibody pairs, optimized monoclonal and polyclonal antibodies, bulk ancillary reagents, and tailored sourcing for rare targets to streamline your assay development pipeline.