Rabbit anti-Human CD200/OX2 Monoclonal Antibody for Flow Cytometry - P41217

Core Product Specifications and Parameters

Biological Background: CD200/OX2 Function and Localization

• OX-2 membrane glycoprotein (CD200) is encoded by the CD200 gene in humans, with aliases MOX1 and MOX2.
• CD200 functions as a costimulatory molecule for T-cell proliferation, enhancing immune responses.
• It may also regulate myeloid cell activity in various tissues, contributing to immune homeostasis.
• CD200 is a cell membrane protein, featuring a single transmembrane helix and an extracellular immunoglobulin domain.
• The protein is noted for alternative splicing, yielding isoforms, and undergoes glycosylation and disulfide bond formation.
• Its signal peptide directs it to the secretory pathway, and it is classified as a transmembrane glycoprotein.

Experimental Guidance and Technical Tips

• This antibody is conjugated to , a red fluorescent dye, suitable for flow cytometry detection.
• The immunogen corresponds to the extracellular domain (amino acids 31-232) of human CD200, ensuring recognition of surface-expressed antigen.
• For flow cytometry, titrate the antibody to determine the optimal staining concentration for your specific cell type.
• Use appropriate isotype controls and live/dead discrimination to ensure specific staining.
• Avoid repeated freeze-thaw cycles; store protected from light to preserve fluorophore stability.

CamelBio: Your One-Stop Sourcing Bridge

As your one-stop IVD raw-material partner, CamelBio offers validated antibody pairs, monoclonal and polyclonal antibodies, and bulk ancillary reagents. For CD200/OX2 studies in immunology and oncology, we provide reliable reagents to accelerate your diagnostic development. Our sourcing network ensures access to rare-target materials from concept to clinic.