Rabbit anti-Human CD2 Monoclonal Antibody for Flow Cytometry - P06729

Core Product Specifications and Parameters

Biological Background: CD2 Function and Localization

• CD2 (T-cell surface antigen CD2), also known as LFA-2, SRBC, and T11, is a cell adhesion molecule belonging to the immunoglobulin superfamily.
• CD2 mediates adhesion between T-cells and other cell types by interacting with lymphocyte function-associated antigens CD58 (LFA-3) and CD48/BCM1.
• The protein is implicated in T-cell triggering, with its cytoplasmic domain playing a role in signal transduction upon engagement.
• CD2 is a single-pass type I membrane protein localized to the cell membrane.
• At the protein level, CD2 is expressed in natural killer cells.
• CD2 contains immunoglobulin-like domains and features structural characteristics including disulfide bonds and glycosylation.
• The predicted molecular weight of the unmodified protein is approximately 39 kDa.

Experimental Guidance and Technical Tips

• As the immunogen comprises the extracellular domain (aa 25-209), this antibody is suitable for detecting cell-surface CD2 by flow cytometry; ensure proper isotype controls are used.
• Fluorescent conjugation with allows direct detection without a secondary antibody; validate signal-to-noise ratios in the relevant experimental system.
• For staining, use standard protocols for live or fixed cells; note that CD2 expression levels may vary among T-cell subsets and activation states.
• This antibody has been raised in rabbit; consider species compatibility when planning multi-color panels.

CamelBio: Your One-Stop Sourcing Bridge

CamelBio supports diagnostic manufacturers, laboratories, and research institutes with comprehensive sourcing of IVD raw materials, technical services, and consulting from concept to clinic. Our portfolio includes validated monoclonal antibodies, such as this anti-CD2 clone, along with recombinant proteins and ancillary reagents for immunoassay development. For CD2-targeted research and diagnostics, we offer one-stop access to bulk antibody production, custom conjugation, and rare target sourcing.