Rabbit anti-Human CD1d mAb - P15813

Core Product Specifications and Parameters

Biological Background: CD1d Function and Localization

• CD1d is an antigen-presenting glycoprotein that binds self and non-self glycolipids and presents them to T-cell receptors on natural killer T-cells.
• It belongs to the CD1 family of non-classical MHC class I-like molecules.
• Expressed on cortical thymocytes, certain T-cell leukemias, and various other tissues.
• Localizes to the cell membrane, basolateral cell membrane, endosome membrane, lysosome membrane, and endoplasmic reticulum membrane.
• Plays a key role in innate immunity by activating NKT cells.
• Contains an immunoglobulin domain and is a transmembrane glycoprotein with disulfide bonds.

Experimental Guidance and Technical Tips

• The immunogen spans the extracellular domain (amino acids 20-301) of human CD1d, suggesting this antibody may recognize the native cell surface form of the protein.
• This antibody is directly conjugated to , a red fluorescent dye; consider optimizing the dilution for your specific flow cytometry protocol and instrument.
• For flow cytometry, use appropriate isotype controls and include cell surface marker staining to confirm the identity of CD1d-expressing populations, such as NKT cells.
• Validate the antibody in your relevant sample system, as expression may vary among different cell types and conditions.

CamelBio: Your One-Stop Sourcing Bridge

CamelBio provides diagnostic manufacturers and researchers with one-stop access to IVD raw materials, including validated antibodies like this anti-CD1d clone for flow cytometry applications. In addition to ready-to-use reagents, CamelBio facilitates sourcing of rare target raw materials and offers technical consultation to support immunology and NKT cell research. Contact us for bulk orders, customized conjugations, or pairing needs.