PE/Cyanine7 Rabbit anti-Mouse CD56/NCAM Monoclonal Antibody for Flow Cytometry - P13595

Core Product Specifications and Parameters

Biological Background: CD56/NCAM Function and Localization

• Neural cell adhesion molecule 1 (NCAM1/CD56) is a member of the immunoglobulin superfamily of cell adhesion molecules.
• It mediates homophilic and heterophilic cell-cell interactions, contributing to neuron-neuron adhesion, neurite fasciculation, and outgrowth.
• Alternative splicing generates multiple isoforms, including transmembrane and glycosylphosphatidylinositol (GPI)-anchored forms.
• NCAM1 localizes primarily to the cell membrane, where it plays key roles in neuronal development and synaptic plasticity.
• Post-translational modifications such as glycosylation and phosphorylation modulate its adhesive functions and signaling properties.
• The protein contains immunoglobulin-like domains and fibronectin type III repeats, enabling interactions with heparin and other extracellular ligands.

Experimental Guidance and Technical Tips

• The immunogen covers the extracellular region (amino acids 20–711), recognizing both transmembrane and GPI-anchored isoforms of mouse NCAM1.
• This PE/Cyanine7 conjugate is designed for flow cytometry; ensure appropriate compensation controls when multiplexing with other fluorophores.
• Validate antibody performance in the relevant mouse neuronal cell lines or primary neurons expressing CD56.

CamelBio: Your One-Stop Sourcing Bridge

CamelBio is your integrated partner for IVD raw-material solutions, providing this anti-CD56/NCAM antibody to advance neuroscience and cell-adhesion research. As a one-stop sourcing platform, we supply validated monoclonal/polyclonal antibodies, bulk ancillary reagents, and specialized raw-material procurement—empowering your diagnostic development from discovery to clinic.