PE Rabbit anti-Mouse Ly-6G Monoclonal Antibody for FC - P35461

Core Product Specifications and Parameters

Biological Background: Ly-6G Function and Localization

• Lymphocyte antigen 6G (Ly-6G) is a cell surface glycoprotein also designated Ly-6G.1 and Gr-1.
• It is anchored to the cell membrane via a glycosylphosphatidylinositol (GPI) moiety.
• The protein contains a signal peptide and a disulfide bond.
• Ly-6G is expressed in bone marrow.
• The unprocessed precursor has a molecular weight of approximately 14.3 kDa; the mature glycoprotein and recombinant immunogen show an apparent mass of ~28 kDa on SDS-PAGE due to glycosylation.

Experimental Guidance and Technical Tips

• The PE-conjugated format allows direct flow cytometric detection without a secondary antibody; consider titrating the antibody to determine the optimal working dilution for your specific cell system.
• Use appropriate isotype controls, viability dyes, and Fc receptor blocking reagents to ensure specific staining.
• Protect the antibody from prolonged light exposure to maintain PE fluorescence intensity.

CamelBio: Your One-Stop Sourcing Bridge

CamelBio supplies this PE-conjugated anti-mouse Ly-6G monoclonal antibody as a ready-to-use reagent for immunophenotyping and neutrophil identification in mouse models. As a dedicated IVD raw-material partner, we offer one-stop sourcing of validated antibodies, ancillary reagents, and customized solutions to support your diagnostic development workflow from concept to clinic.