Monoclonal Antibodies
PE Rabbit anti-Mouse CD96/TACTILE Monoclonal Antibody for Flow Cytometry - Q3U0X8
Item Number : CM0012427
Price varies based on specs and customizations
- Application
- FC
- Cross Reactivity
- Mouse
- Protein Weight
- 67kDa
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Core Product Specifications and Parameters
| Parameter | Value |
|---|---|
| Product Name | PE Rabbit anti-Mouse CD96/TACTILE mAb |
| Remarks/Alias | Tactile; 1700109I12Rik |
| Species | Mouse |
| Gene ID (Human) | 10225 |
| Gene ID | 84544 |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 35-536 of mouse CD96/TACTILE (NP_115854.2). |
| Source | Rabbit |
| Category | Monoclonal Antibodies |
| Application | FC |
| Cross Reactivity | Mouse |
| SWISS | Q3U0X8 |
| Protein Weight | 67kDa |
| Shipping | Ice bag |
Biological Background: CD96/TACTILE Function and Localization
- T-cell surface protein tactile (CD96) is a membrane glycoprotein belonging to the immunoglobulin superfamily, containing Ig-like domains and a transmembrane helix.
- It is expressed on activated T and NK cells and functions in cell adhesion by interacting with PVR (CD155) on target cells, promoting NK cell-target adhesion.
- CD96 may be involved in the late phase of immune response, after leukocyte extravasation, facilitating engagement with diseased cells within inflamed tissues (By similarity).
- The protein undergoes post-translational modifications including disulfide bond formation and N-linked glycosylation, which are critical for its structural stability and function.
- As a member of the CD96 family, it plays a role in immune surveillance and regulation of innate and adaptive immunity.
Experimental Guidance and Technical Tips
- The immunogen covers the entire extracellular domain (amino acids 35-536), suggesting the antibody recognizes native protein conformation; confirm reactivity in relevant mouse T and NK cell populations.
- For flow cytometry, use a PE-conjugated isotype control and titrate the antibody to determine the optimal staining concentration for your cell type and experimental conditions.
- This antibody is validated for FC; consider validating in your specific assay system if using it for other applications, as performance may vary.
CamelBio: Your One-Stop Sourcing Bridge
CamelBio supports diagnostic manufacturers and research teams with a comprehensive portfolio of IVD raw materials, including validated antibody pairs, optimized monoclonal and polyclonal antibodies, and bulk ancillary reagents. For immune checkpoint and cell adhesion targets like CD96/TACTILE, our sourcing network can help you secure rare target reagents and custom solutions to accelerate your development pipeline. Reach out to discuss how we can fulfill your raw material requirements with reliable supply and technical support.
Product Datasheet
PE Rabbit anti-Mouse CD96/TACTILE Monoclonal Antibody for Flow Cytometry - Q3U0X8
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