PE Rabbit anti-Mouse CD200/OX2 Monoclonal Antibody for FC - O54901

Core Product Specifications and Parameters

Biological Background: CD200/OX2 Function and Localization

• OX-2 membrane glycoprotein (CD200, also known as MRC OX-2 antigen) is encoded by the Cd200 gene (also designated Mox2) and belongs to the immunoglobulin superfamily.
• CD200 functions as a costimulator of T-cell proliferation and may regulate myeloid cell activity in a variety of tissues.
• The protein is localized to the cell membrane as a single-pass type I membrane protein.
• Structural features include an immunoglobulin domain, a disulfide bond, and N-linked glycosylation sites; the mature protein has a molecular weight of approximately 31 kDa.
• Post-translational modifications and structural data are available, including a 3D structure entry.

Experimental Guidance and Technical Tips

• The immunogen covers the extracellular region (amino acids 31–232), making this antibody well-suited for detecting cell surface CD200 in flow cytometry.
• Because it is directly conjugated to PE, no secondary antibody is needed, which simplifies staining protocols and reduces background.
• Consider validating staining patterns on mouse immune cells (e.g., myeloid lineages, activated T cells) known to express CD200/OX2.
• When designing multicolor panels, include appropriate isotype controls and use live/dead discrimination for accurate gating.

CamelBio: Your One-Stop Sourcing Bridge

CamelBio provides diagnostic manufacturers and researchers with streamlined access to this PE anti-mouse CD200/OX2 monoclonal antibody as part of a one-stop IVD raw material sourcing solution. Our portfolio includes validated antibody pairs, optimized monoclonal/polyclonal antibodies, and bulk ancillary reagents to support your immunology and diagnostic programs. Whatever your development stage—from concept to clinic—we help you secure the right raw materials efficiently.