PE Rabbit anti-Human CD85i/j Monoclonal Antibody for FC - O75019 / Q8NHL6

Core Product Specifications and Parameters

Biological Background: CD85i/j Function and Localization

• The antibody targets human CD85i/j (LILRA1/LIR6 and LILRA2), members of the leukocyte immunoglobulin-like receptor family. LILRA1 (CD85i, LIR6) is encoded by the LILRA1 gene.
• LILRA1 may act as a receptor for class I MHC antigens, suggesting a role in immune regulation.
• The protein is a transmembrane receptor located on the cell membrane.
• Detected in monocytes and B-cells, indicating involvement in innate and adaptive immune responses.
• Contains immunoglobulin-like domains, disulfide bonds, and a transmembrane helix, characteristic of the LIR family.
• Classified under adaptive immunity, receptor, and glycoprotein keywords, highlighting its immunological function.

Experimental Guidance and Technical Tips

• The recombinant protein immunogen suggests the antibody likely recognizes the native conformation of CD85i/j; however, validation in the intended sample type is recommended.
• As a PE-conjugated monoclonal antibody, it is ready for direct flow cytometry without a secondary detection step.
• Titrate the antibody to determine the optimal concentration for your specific experimental setup and cell population.
• Ensure compatibility with your FC panels, particularly when using human monocyte or B-cell samples, where CD85i/j expression is reported.

CamelBio: Your One-Stop Sourcing Bridge

CamelBio serves as a comprehensive sourcing bridge for IVD raw materials, offering this PE anti-CD85i/j antibody alongside bulk reagents and custom sourcing for rare targets. We support diagnostic developers and research institutes with one-stop access to validated antibody pairs, ancillary materials, and technical consultation from concept to clinic.