PE Rabbit anti-Human CD213a1/IL-13Rα1 Monoclonal Antibody for Flow Cytometry - P78552

Core Product Specifications and Parameters

Biological Background: IL13RA1 Function and Localization

• IL13RA1 encodes the interleukin-13 receptor subunit alpha-1, also known as cancer/testis antigen 19 (CT19).
• Binds IL13 with low affinity; together with IL4RA forms a functional receptor for IL13.
• Serves as an alternate accessory protein to the common cytokine receptor gamma chain for IL4 signaling, but cannot replace IL2RG in allowing enhanced IL2 binding.
• Ubiquitously expressed, with highest levels in heart, liver, skeletal muscle, and ovary; lowest in brain, lung, and kidney. Also present on B-cells, T-cells, and endothelial cells.
• Membrane-localized receptor with a signal peptide, disulfide bonds, glycosylation, and a transmembrane helix.
• Keywords: 3D-structure, Alternative splicing, Disulfide bond, Glycoprotein, Membrane, Proteomics identification, Receptor, Reference proteome, Repeat, Signal, Transmembrane, Transmembrane helix.

Experimental Guidance and Technical Tips

• The immunogen encompasses the extracellular domain (amino acids 29-343), suggesting the antibody targets an extracellular epitope, suitable for flow cytometry with live unfixed cells.
• Validate antibody reactivity with known CD213a1-expressing human cell lines or primary cells such as B-cells and T-cells.
• Use appropriate isotype control antibodies conjugated to PE for accurate flow cytometry gating.
• Since the antibody is PE-conjugated, ensure compensation controls are set up correctly for multicolor panels.

CamelBio: Your One-Stop Sourcing Bridge

CamelBio provides diagnostic manufacturers, labs, and research institutes with one-stop access to IVD raw materials, technical services, and consulting—covering every stage from concept to clinic. This anti-IL13RA1 monoclonal antibody is suitable for flow cytometry applications in immunology and cancer research. Contact us for bulk supply, custom conjugation, and additional formulation services.