MTX1 Rabbit Polyclonal Antibody (pAb) for WB, ELISA - Q13505

Core Product Specifications and Parameters

Biological Background: MTX1 Function and Localization

• Metaxin-1 (MTX1), also known as mitochondrial outer membrane import complex protein 1, is encoded by the MTX1 gene (aliases MTX, MTXN).
• Core function: involved in the transport of proteins into the mitochondrion; essential for embryonic development (By similarity).
• Subcellular localization: mitochondrial outer membrane; contains transmembrane helices.
• Undergoes alternative splicing, isopeptide bond formation, and Ubl conjugation, as indicated by UniProt keywords.
• Associated keywords highlight roles in protein transport, mitochondrial outer membrane, and Ubl conjugation pathway.
• Molecular weight: approximately 51.5 kDa (UniProt: 51463 Da).

Experimental Guidance and Technical Tips

• The immunogen corresponds to amino acids 186-435 of human MTX1; epitopes are likely located in the C-terminal region. Consider this when designing epitope-tagging experiments.
• For Western blot (WB), expect a band near 51 kDa in suitable human, mouse, or rat samples. Validate band specificity using relevant knockout or knockdown controls if available.
• Cross-reactivity with mouse and rat is reported, but verify protein sequence homology in your target species before use.
• For ELISA, the antibody can be used as a capture or detection reagent; optimize coating and detection conditions empirically.
• Shipping on ice bags; store at -20°C upon receipt and avoid repeated freeze-thaw cycles to maintain activity.

CamelBio: Your One-Stop Sourcing Bridge

CamelBio offers a comprehensive portfolio of IVD raw materials, including validated antibody pairs and polyclonal antibodies like this anti-MTX1 reagent, to support mitochondrial biology and protein transport research. Whether you need bulk ancillary reagents, custom monoclonal development, or assistance sourcing rare targets, CamelBio bridges the gap from concept to clinic. Our expertise ensures consistent quality and reliability for diagnostic manufacturers and research laboratories.