MRPL45 Rabbit Polyclonal Antibody for WB, IHC-P, IF/ICC, ELISA - Q9BRJ2

Core Product Specifications and Parameters

Biological Background: MRPL45 Function and Localization

• MRPL45, also known as 39S ribosomal protein L45, mitochondrial (L45mt or MRP-L45), is a component of the mitochondrial large ribosomal subunit (mt-LSU). Related references: PMID:25278503, PMID:25838379, PMID:28892042
• Within the mitochondrial ribosome, MRPL45 directs the nascent polypeptide toward the tunnel exit and positions the exit at a distance from the membrane surface. Related references: PMID:33602856
• MRPL45 localizes to the mitochondrion, consistent with its role in mitochondrial protein synthesis.
• Encoded by the MRPL45 gene, this protein contains a transit peptide for mitochondrial import and is classified as a ribosomal protein and ribonucleoprotein.

Experimental Guidance and Technical Tips

• The immunogen, a recombinant fusion protein covering amino acids 57–306 of human MRPL45, is expected to elicit polyclonal antibodies against multiple epitopes, supporting robust performance in WB, IHC-P, IF/ICC, and ELISA.
• For WB, a band at approximately 35 kDa is expected; however, validate molecular weight in your sample system due to potential post‑translational modifications or processing.
• Based on sequence homology, cross‑reactivity with mouse and rat is anticipated. It is advisable to confirm reactivity in relevant species‑specific lysates or tissue sections.

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CamelBio offers diagnostic manufacturers, labs, and research institutes streamlined access to high‑quality IVD raw materials like this MRPL45 antibody, supporting mitochondrial and ribosome research. Our comprehensive portfolio includes validated antibody pairs, optimized monoclonal and polyclonal antibodies, bulk ancillary reagents, and custom sourcing for rare targets. Let us help accelerate your development from concept to clinic with reliable supply solutions.