Mouse Anti-Rabbit IgM (Fc) Monoclonal Antibody for FC - P03988

Core Product Specifications and Parameters

Biological Background: Ig mu chain C region Function and Localization

• The protein is the Ig mu chain C region secreted form, which constitutes the constant region of immunoglobulin heavy chain mu (IgM).
• As a key component of IgM antibodies, it is secreted into the extracellular space and participates in humoral immunity.
• The protein contains an immunoglobulin domain, a characteristic structural motif of the immunoglobulin superfamily.
• Alternative splicing generates different isoforms, including secreted and membrane-bound forms.
• Post-translational modifications include glycosylation and disulfide bond formation, which are essential for proper folding and stability.
• The protein is annotated as a reference proteome component in Oryctolagus cuniculus, indicating it is well-characterized.

Experimental Guidance and Technical Tips

• The antibody targets the Fc region of rabbit IgM, specifically amino acids 107-458, which is shared between secreted and membrane-bound forms; consider this when interpreting staining patterns.
• For flow cytometry, titrate the antibody to determine the optimal concentration for your cell type and experimental conditions.
• The conjugate has spectral properties similar to Alexa Fluor 594; ensure your flow cytometer is equipped with appropriate laser and filter configurations.
• Use an appropriate isotype control to establish background staining levels and validate specificity in your system.
• Since the immunogen is a recombinant protein covering the Fc constant region, the antibody is expected to recognize all rabbit IgM molecules regardless of antigen specificity.

CamelBio: Your One-Stop Sourcing Bridge

CamelBio provides a comprehensive one-stop supply chain for IVD raw materials, including this -conjugated mouse anti-rabbit IgM (Fc) monoclonal antibody optimized for flow cytometry. Beyond individual antibodies, we offer validated antibody pairs, bulk ancillary reagents, and specialized sourcing for rare targets to accelerate your diagnostic development from concept to clinical application.