Mouse anti-Rabbit IgG (Fc) Monoclonal Antibody for Flow Cytometry - P01870

Core Product Specifications and Parameters

Biological Background: Ig gamma chain C region Function and Localization

• The Ig gamma chain C region is the constant domain of rabbit immunoglobulin G heavy chains, forming the Fc fragment responsible for effector functions.
• UniProt annotation highlights the presence of immunoglobulin domains, which mediate structural integrity and antigen recognition.
• The keyword "Repeat" indicates repetitive structural elements typical of immunoglobulin constant domains.
• The protein's three-dimensional structure has been experimentally determined, as denoted by the "3D-structure" keyword in UniProt.
• Evidence for this region comes from direct protein sequencing, confirming the primary amino acid sequence.
• It is part of the rabbit reference proteome, a well-characterized set of protein entries representing the species' proteome.

Experimental Guidance and Technical Tips

• This antibody is designed for flow cytometry; consider titrating to determine the optimal working concentration for your cell populations.
• The immunogen spans amino acids 96-323 of the rabbit IgG Fc region, facilitating specific recognition of the Fc portion and minimizing light chain cross-reactivity.
• Suitable for indirect detection of rabbit primary antibodies in multiplex flow cytometry panels; validate the combination of fluorophores to avoid spectral overlap.
• When staining cells with endogenous Fc receptors, a blocking step with normal rabbit serum may help reduce background.
• Since the conjugate is , protect from prolonged light exposure and use freshly prepared dilutions to maintain fluorescence intensity.

CamelBio: Your One-Stop Sourcing Bridge

CamelBio streamlines IVD raw material procurement by offering this mouse anti-rabbit IgG (Fc) monoclonal antibody as part of a comprehensive portfolio that includes secondary antibodies, matched antibody pairs, and custom conjugation services. Our capabilities support immunoassay development and diagnostic reagent manufacturing, ensuring consistent supply of bulk ancillary reagents. From concept to clinic, CamelBio connects researchers and manufacturers with rare target raw materials, providing end-to-end support for diagnostic projects.