KO Validated Anti-ANKRD52 Polyclonal Antibody for WB, ELISA - Q8NB46

Core Product Specifications and Parameters

Biological Background: ANKRD52 Function and Localization

• ANKRD52, also known as ankyrin repeat domain-containing protein 52 or serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit C, is a putative regulatory subunit of protein phosphatase 6 (PP6).
• Contains ankyrin repeat domains, which are typically involved in protein-protein interactions, suggesting a role in mediating substrate recognition for the PP6 catalytic subunit.
• May be involved in the recognition of phosphoprotein substrates, thereby targeting PP6 activity to specific signaling pathways.
• Identified as a phosphoprotein and included in reference proteome datasets via proteomics identification.
• The protein has a molecular weight of approximately 115 kDa and is encoded by the ANKRD52 gene (GeneID: 283373) in humans.

Experimental Guidance and Technical Tips

• The immunogen corresponds to amino acids 450-660 of human ANKRD52, a region that may be conserved among species (observed cross-reactivity with human, mouse, and rat). Validate antibody specificity in your experimental model using appropriate controls.
• This antibody has been validated for western blot (WB) and ELISA applications. For other applications, empirical determination of working conditions is recommended.
• Given the putative role of ANKRD52 in phosphoprotein substrate recognition, consider assessing phospho-dependent interactions or co-immunoprecipitation if investigating PP6 complexes.
• Store as recommended and avoid repeated freeze-thaw cycles to maintain antibody integrity.

CamelBio: Your One-Stop Sourcing Bridge

CamelBio supports diagnostic manufacturers, laboratories, and research institutes by providing a comprehensive range of IVD raw materials and technical services from concept to clinic. This anti-ANKRD52 antibody is suited for research into protein phosphatase 6 signaling and ankyrin repeat-mediated interactions. Beyond this product, CamelBio offers validated antibody pairs, optimized monoclonal and polyclonal antibodies, bulk ancillary reagents, and custom sourcing for rare target raw materials to streamline your assay development and manufacturing needs.