KO Validated Anti-ABCF2 Rabbit Polyclonal Antibody for WB, ELISA - Q9UG63

Core Product Specifications and Parameters

Biological Background: ABCF2 Function and Localization

• ABCF2 (ATP-binding cassette sub-family F member 2) is encoded by the ABCF2 gene (GeneID: 10061) and is also known as Iron-inhibited ABC transporter 2.
• It belongs to the ABC transporter superfamily, containing two nucleotide-binding domains (NBDs) as indicated by the Keywords "ATP-binding", "Nucleotide-binding", and "Repeat".
• The protein is subject to alternative splicing, acetylation, and phosphorylation, as annotated in UniProt (Keywords: Alternative splicing, Acetylation, Phosphoprotein).
• ABCF2 is part of the reference proteome, ensuring its representation of a canonical human protein.

Experimental Guidance and Technical Tips

• The immunogen spans amino acids 1-250 of human ABCF2 (N-terminal region), so the antibody likely recognizes epitopes within this fragment; consider epitope competition for critical applications.
• Validated for Western blot (WB) and ELISA; for WB, use whole-cell lysates from human, mouse, or rat samples. Expected band ~71 kDa.
• This antibody is KO Validated, indicating specificity confirmed by knockout models; validate in your own system with appropriate positive and negative controls.
• As a polyclonal antibody, lot-to-lot variability may occur; titrate for optimal dilution and validate consistency.
• For ELISA, optimize antigen coating and detection conditions; cross-reactivity with mouse and rat enables species-flexible assay design.

CamelBio: Your One-Stop Sourcing Bridge

CamelBio streamlines IVD raw material procurement for diagnostic developers, offering validated antibody pairs, monoclonal/polyclonal antibodies, ancillary reagents, and rare-target sourcing. This anti-ABCF2 rabbit polyclonal antibody supports research into ABC transporter function and related disorders, and CamelBio can assist in scaling up supply or customizing formats to meet your project’s needs from concept to clinic.