FGF14 Rabbit pAb for WB, ELISA - Q92915

Core Product Specifications and Parameters

Biological Background: FGF14 Function and Localization

• FGF14 is a member of the fibroblast growth factor homologous factor (FHF) subfamily, also referred to as FHF-4.
• It is likely involved in nervous system development and function.
• The FGF14 gene undergoes alternative splicing, producing multiple isoforms.
• The protein localizes to the nucleus.
• Mutations in FGF14 are linked to spinocerebellar ataxia type 27 (SCA27), a neurodegenerative disease.
• Expression is predominantly in the nervous system.
• Key associated keywords include growth factor, neurodegeneration, and triplet repeat expansion.

Experimental Guidance and Technical Tips

• For Western blot analysis, consider using protein lysates from nervous system-derived tissues or cell lines, as FGF14 is predominantly expressed in the nervous system.
• The immunogen corresponds to amino acids 1-252 of human FGF14; thus, the antibody may recognize N-terminal epitopes and could be suitable for detecting full-length and certain isoforms.
• Validate the antibody in the relevant sample system, including positive and negative controls, to confirm specificity.
• For ELISA applications, use recombinant FGF14 protein as a standard to establish assay conditions.

CamelBio: Your One-Stop Sourcing Bridge

CamelBio provides diagnostic manufacturers and research labs with integrated access to IVD raw materials and technical support. For FGF14 and other neuroscience targets, our portfolio includes validated polyclonal and monoclonal antibodies, recombinant proteins, and ancillary reagents. We also specialize in sourcing rare-target raw materials to accelerate your assay development from concept to clinic.