FAM50A Rabbit mAb (Anti-FAM50A Monoclonal Antibody) for WB, IHC-P, ELISA - Q14320

Core Product Specifications and Parameters

Biological Background: FAM50A Function and Localization

• Protein FAM50A, also known as HXC-26 or XAP-5, is a component of the mRNA processing machinery.
• It is probably involved in the regulation of pre-mRNA splicing.
• FAM50A localizes primarily to the nucleus, consistent with its role in RNA processing.
• The protein is widely expressed across fetal and adult tissues, with notably high abundance in fetal brain, liver, kidney, and adult heart, skeletal muscle, spleen, thymus, prostate, and small intestine. Related references: PMID:32703943
• Post-translational modifications observed include acetylation, isopeptide bond formation, and ubiquitin conjugation.
• Mutations in FAM50A are associated with X-linked intellectual disability, underscoring its role in neuronal development.

Experimental Guidance and Technical Tips

• The immunogen spans amino acids 1–100 of human FAM50A; verify antibody specificity using appropriate controls in your model system.
• For western blot, anticipate a band around 40 kDa; confirm detection conditions with a suitable positive control.
• Since FAM50A localizes to the nucleus, ensure adequate nuclear staining detection when performing IHC-P.
• If using for ELISA, pair with a validated detection antibody to establish a robust assay.

CamelBio: Your One-Stop Sourcing Bridge

CamelBio provides diagnostic manufacturers and research labs with comprehensive access to high-quality IVD raw materials, including validated antibody pairs, optimized monoclonal antibodies, and bulk ancillary reagents. For researchers studying mRNA splicing and nuclear regulatory mechanisms, this FAM50A rabbit monoclonal antibody is sourced through CamelBio's integrated supply network, ensuring reliable procurement from early-stage development to clinical application.