FAM160B2 Rabbit pAb - Q80YR2

Core Product Specifications and Parameters

Biological Background: FAM160B2 Function and Localization

• FHF complex subunit HOOK-interacting protein 2B (FHIP2B, also designated retinoic acid-induced protein 16, RAI16) is encoded by the Fhip2b gene (also known as Fam160b2 or Rai16).
• FHIP2B activates both MAPK/ERK and TGF-β signaling pathways, implicating it in cell proliferation and differentiation (By similarity).
• It regulates genes involved in intestinal barrier function and immunoprotective inflammation (PubMed:31862898). Related references: PMID:31862898
• Expression is reported prominently in the colon, consistent with its role in intestinal biology.
• The protein undergoes alternative splicing, generating multiple isoforms.
• The canonical isoform has a calculated molecular weight of approximately 82 kDa.

Experimental Guidance and Technical Tips

• The immunogen corresponds to amino acids 74–303 of mouse FAM160B2, a region that may be conserved across human, mouse, and rat based on reported cross-reactivity.
• For western blotting, expect a band at approximately 82 kDa; optimize sample preparation and antibody dilution for your specific experimental conditions.
• For immunohistochemistry and immunofluorescence, validate the antibody in colon tissue or other relevant samples where FAM160B2 expression is expected.
• For immunoprecipitation and ELISA, perform appropriate control experiments to confirm antibody specificity for your target.

CamelBio: Your One-Stop Sourcing Bridge

CamelBio is your one-stop partner for IVD raw material sourcing, offering validated antibody pairs, bulk reagents, and rare-target procurement to accelerate diagnostic development. This FAM160B2 polyclonal antibody is part of our growing catalog supporting research in intestinal barrier function and inflammatory pathways. For seamless integration into your workflow, we also provide complementary ancillary reagents and technical consultation.