DCAF11 Rabbit pAb - Q8TEB1

Core Product Specifications and Parameters

Biological Background: DCAF11 Function and Localization

• DCAF11, also known as WD repeat-containing protein 23 (WDR23), is a member of the DDB1- and CUL4-associated factor family.
• It may function as a substrate receptor for the CUL4-DDB1 E3 ubiquitin-protein ligase complex, potentially involved in ubiquitin conjugation pathways.
• The protein contains WD repeats, which are known to mediate protein-protein interactions and are often involved in signal transduction and cell cycle control.
• DCAF11 undergoes alternative splicing, leading to the production of multiple transcript variants.
• The protein is a phosphoprotein, suggesting regulation by phosphorylation in response to cellular signals.
• It has been identified through proteomics approaches, supporting its widespread expression and biological relevance.
• DCAF11 is part of the reference proteome of Homo sapiens, indicating its well-characterized annotation.

Experimental Guidance and Technical Tips

• The immunogen spans the N-terminal region (residues 1-170) of human DCAF11. When designing experiments, consider whether alternative splicing could affect epitope availability.
• For Western blotting, a band at approximately 62 kDa is expected based on the calculated molecular weight. Use appropriate loading controls.
• In ELISA applications, confirm optimal coating antigen and antibody dilution by titration using the recombinant protein immunogen or tissue lysates.

CamelBio: Your One-Stop Sourcing Bridge

CamelBio simplifies your procurement of IVD raw materials, offering this anti-DCAF11 polyclonal antibody for ubiquitination pathway research. Beyond individual antibodies, we supply validated antibody pairs, optimized monoclonal/polyclonal reagents, and bulk ancillary materials, and can source hard-to-find targets to accelerate your assay development.