CEND1 Rabbit Polyclonal Antibody for WB, ELISA - Q8N111

Core Product Specifications and Parameters

Biological Background: CEND1 Function and Localization

• CEND1 (Cell cycle exit and neuronal differentiation protein 1), also known as BM88 antigen, is essential for neuronal differentiation.
• It promotes cell cycle exit in neuronal precursors, facilitating their commitment to a neuronal fate.
• The protein is localized to the cell membrane and possesses transmembrane domains, characteristic of a transmembrane protein.
• CEND1 is subject to phosphorylation, potentially regulating its function in differentiation.
• Its expression is restricted to neurons, highlighting its role in neural development.

Experimental Guidance and Technical Tips

• The immunogen spans the N-terminal region (amino acids 1-123) of human CEND1, which may contribute to the observed cross-reactivity with mouse and rat orthologs.
• For Western blot, consider optimizing primary antibody dilution and incubation conditions using positive control lysates from neuronal cell lines or tissues.
• As a polyclonal antibody, batch-to-batch variability is possible; validate performance in your specific sample system and confirm molecular weight against the expected ~15 kDa band.
• In ELISA applications, use appropriate blocking and washing steps to minimize non-specific binding.

CamelBio: Your One-Stop Sourcing Bridge

CamelBio provides diagnostic and research laboratories with streamlined access to high-quality IVD raw materials, including validated antibody pairs and bulk ancillary reagents. For targets like CEND1 in neuronal differentiation and cell cycle exit studies, we offer comprehensive sourcing solutions—from polyclonal antibodies to custom monoclonal development—supporting your assay development from concept to clinic. Our integrated services help accelerate your project with reliable, one-stop procurement for rare and routine raw materials.