CDV3 Rabbit Polyclonal Antibody for WB, IF/ICC, ELISA - Q9UKY7

Core Product Specifications and Parameters

Biological Background: CDV3 Function and Localization

• CDV3, also known as H41, is a human protein encoded by the CDV3 gene (GeneID: 55573).
• The protein is primarily localized to the cytoplasm, as indicated by subcellular location annotations.
• CDV3 undergoes alternative splicing, producing multiple transcript variants that may have distinct functions.
• Tissue specificity studies show that CDV3 expression levels correlate with HER-2/neu levels in breast cancer cells, suggesting a potential role in cancer biology.
• Post-translational modifications, including acetylation and phosphorylation, have been reported and may regulate CDV3 activity.
• CDV3 has been identified in high-throughput proteomics analyses as part of the human reference proteome.
• The predicted molecular weight of CDV3 is approximately 27 kDa (27335 Da), consistent with the observed band in western blotting.

Experimental Guidance and Technical Tips

• This polyclonal antibody was generated against a synthetic peptide within amino acids 150–250 of human CDV3. For western blot, consider starting with a dilution range of 1:500–1:2000 and optimize to detect the expected band near 27 kDa.
• For immunofluorescence/immunocytochemistry, fixation and permeabilization conditions should be validated to preserve the cytoplasmic localization of CDV3.
• In ELISA, the immunogen peptide can serve as a positive control to assess antibody binding efficiency.
• Cross-reactivity with mouse and rat has been reported; it is advisable to confirm specificity in your experimental model when performing comparative studies.
• As with any polyclonal antibody, lot-to-lot variability may exist—include appropriate controls to ensure consistent results.

CamelBio: Your One-Stop Sourcing Bridge

CamelBio supports diagnostic manufacturers and research laboratories with a comprehensive portfolio of IVD raw materials and technical services. For researchers investigating CDV3 and its role in cancer biology, we offer reliable supply chains for validated antibody pairs, bulk polyclonal antibodies, and ancillary reagents. Our one-stop sourcing platform streamlines procurement from concept to clinic, helping you accelerate assay development and translational research.