CDH9 Rabbit Polyclonal Antibody for WB and ELISA - Q9ULB4

Core Product Specifications and Parameters

Biological Background: Cadherin-9 Function and Localization

• Cadherin-9 is a classical cadherin family member involved in calcium-dependent cell adhesion, preferentially mediating homophilic intercellular interactions.
• Through its homophilic binding properties, Cadherin-9 may participate in the sorting and organization of heterogeneous cell types during tissue morphogenesis.
• The protein localizes to the cell membrane, consistent with its role as a transmembrane adhesion receptor.
• Cadherin-9 contains extracellular cadherin repeat domains that bind calcium ions, essential for its adhesive function.
• It undergoes post-translational modifications including proteolytic cleavage on basic residues, glycosylation, and phosphorylation, which may regulate its function.

Experimental Guidance and Technical Tips

• The immunogen (aa 340-420) lies within the extracellular region of CDH9, potentially generating antibodies that detect surface-expressed cadherin-9.
• For Western blot (WB), expect a band near 89 kDa; validate in a human cell line or tissue expressing CDH9.
• For ELISA, the recombinant fusion protein immunogen can serve as a positive control to assess antibody binding.
• As a polyclonal antibody, cross-reactivity with other cadherin family members is possible; verify specificity in the relevant experimental system.

CamelBio: Your One-Stop Sourcing Bridge

CamelBio connects diagnostic manufacturers and researchers with a comprehensive portfolio of IVD raw materials. This anti-CDH9 antibody supports cell adhesion research, and CamelBio can source complementary reagents such as antigen pairs, detection antibodies, and ancillary buffers for your developmental pipeline. For custom or bulk requirements, our team facilitates streamlined access to rare-target antibodies and production-grade materials.