APC Rabbit anti-Mouse IgG1 Monoclonal Antibody for FC - P01868

Core Product Specifications and Parameters

Biological Background: IgG1 Function and Localization

• Ig gamma-1 chain C region secreted form, encoded by Ighg1 (Igh-4), constitutes the constant region of mouse IgG1 immunoglobulin.
• Alternative splicing generates the secreted isoform, enabling its role in humoral immunity.
• Subcellular localization: secreted into extracellular space and body fluids.
• Structural features: contains an immunoglobulin domain, disulfide bonds, and glycosylation sites.
• The protein has been characterized by 3D structure determination and direct protein sequencing.
• It is included in the mouse reference proteome.

Experimental Guidance and Technical Tips

• The immunogen spans the constant region (aa 98-324), suggesting the antibody recognizes the constant domain independent of variable region specificity.
• For flow cytometry, titrate the antibody to determine the optimal staining concentration for your cell population, and use an appropriate isotype control.
• Validate performance in your specific sample matrix, as fixation and permeabilization may affect epitope accessibility.
• Consider multiplex isotyping panels by combining with other anti-mouse immunoglobulin reagents.

CamelBio: Your One-Stop Sourcing Bridge

CamelBio is your integrated partner for IVD raw material sourcing, providing diagnostic manufacturers and researchers with streamlined access to high-quality antibodies and reagents. This APC-conjugated anti-mouse IgG1 monoclonal antibody supports flow cytometry and immunoassay development. Explore our catalog for validated antibody pairs, bulk reagent options, and custom sourcing solutions to accelerate your diagnostic projects.