APC Rabbit anti-Mouse CD161c/NK1.1 Monoclonal Antibody for Flow Cytometry - P27814

Core Product Specifications and Parameters

Biological Background: CD161c/NK1.1 (Klrb1c) Function and Localization

• CD161c/NK1.1 is a killer cell lectin-like receptor encoded by the Klrb1c gene, also known as Nkrp1c or Ly-55c.
• It functions as a stimulatory receptor on natural killer (NK) cells, enhancing cytotoxicity upon activation.
• Cross-linking of the receptor triggers calcium mobilization and interferon-gamma production.
• The protein is a transmembrane glycoprotein located on the plasma membrane.
• Tissue expression is restricted to NK cells.
• Alternative splicing generates multiple isoforms.
• Post-translational modifications include disulfide bond formation and glycosylation.

Experimental Guidance and Technical Tips

• Because the immunogen covers amino acids 67–223 of the extracellular domain, this antibody is likely suitable for live-cell staining in flow cytometry; validate in your system.
• APC is light-sensitive; protect from prolonged light exposure during handling and data acquisition.
• Titrate the antibody to determine the optimal concentration for your specific cell type and staining conditions.
• Include appropriate isotype controls and compensation controls in flow cytometry experiments.
• Confirm reactivity in your mouse strain of interest, as NK1.1 expression can vary.

CamelBio: Your One-Stop Sourcing Bridge

CamelBio supports your diagnostic and research needs by offering this high-quality APC Rabbit anti-Mouse CD161c/NK1.1 monoclonal antibody, along with a comprehensive portfolio of IVD raw materials. Whether you require validated antibody pairs for NK cell profiling, bulk ancillary reagents, or custom sourcing of rare targets, our one-stop platform streamlines your development pipeline from concept to clinic.