APC Rabbit anti-Human CD45RB Monoclonal Antibody for FC - P08575-9

Core Product Specifications and Parameters

Biological Background: CD45RB Function and Localization

• CD45RB represents one of several alternative splice isoforms of the receptor-type tyrosine-protein phosphatase C, encoded by the PTPRC (CD45) gene.
• Commonly referred to as leukocyte common antigen (L-CA) or T200, the protein is abundantly expressed on the surface of nucleated hematopoietic cells.
• This isoform (isoform 7) has a predicted molecular weight of approximately 135.7 kDa.
• The protein is classified as a receptor-type tyrosine-protein phosphatase, featuring an intracellular catalytic domain.

Experimental Guidance and Technical Tips

• For flow cytometry (FC), titrate the antibody to determine the optimal staining concentration for your specific cell type and experimental conditions.
• Verify reactivity in your human sample system, as cross-reactivity has been demonstrated for human only.
• As an APC conjugate, protect the antibody from light and avoid repeated freeze-thaw cycles; store at 2–8°C upon receipt.
• Include appropriate isotype controls and assess fluorescence compensation settings to ensure reliable data interpretation.

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CamelBio streamlines the procurement of IVD raw materials, providing access to validated antibodies like this APC-conjugated anti-CD45RB clone for flow cytometry applications. We support diagnostic manufacturers and researchers with bulk monoclonal antibodies, antibody pairs, and customized sourcing for rare targets. Partner with us to simplify your supply chain from concept to clinic.