Anti-ZNF621 Polyclonal Antibody for WB, ELISA - Q6ZSS3

Core Product Specifications and Parameters

Biological Background: ZNF621 Function and Localization

• ZNF621 belongs to the zinc finger protein family, which is characterized by the presence of zinc finger domains that typically facilitate DNA binding and transcriptional regulation.
• The protein is predicted to act as a transcription factor, potentially modulating the expression of target genes.
• Zinc finger proteins often function in development, differentiation, and cellular response pathways, though the precise role of ZNF621 remains to be fully elucidated.
• Consistent with its putative role in transcription, ZNF621 localizes to the nucleus.
• The protein contains multiple conserved zinc finger motifs, which bind zinc ions and stabilize the DNA-binding structure.
• Alternative splicing has been observed for ZNF621, which may generate isoforms with distinct regulatory properties.
• The full-length ZNF621 has a predicted molecular weight of approximately 49 kDa, though post-translational modifications may alter its apparent size on SDS-PAGE.

Experimental Guidance and Technical Tips

• The immunogen used comprises amino acids 60–150 of human ZNF621, an internal region; this antibody may detect multiple isoforms containing this sequence.
• For Western blot, a band near 49 kDa is anticipated; however, verify the observed size in your specific sample system.
• ZNF621 may be expressed at low levels; consider enriching nuclear fractions or using cell lines with known expression for optimal detection.
• ELISA applications should include appropriate controls and optimize coating and detection conditions.
• If using this antibody for immunoprecipitation or other untested applications, preliminary validation is advised.

CamelBio: Your One-Stop Sourcing Bridge

CamelBio is dedicated to supporting diagnostic manufacturers, laboratories, and research institutes with a comprehensive portfolio of IVD raw materials, technical services, and consulting for every development stage. This ZNF621 polyclonal antibody is offered as part of our transcription research tools, and we also supply validated antibody pairs, optimized monoclonal/polyclonal antibodies, and bulk ancillary reagents. For rare target raw-material sourcing or custom requirements, our team is here to assist as your one-stop procurement partner.