Anti-ZNF587 Rabbit Polyclonal Antibody for WB, ELISA - Q96SQ5

Core Product Specifications and Parameters

Biological Background: ZNF587 Function and Localization

• ZNF587 is a zinc finger protein encoded by the ZNF587 gene; alternative splicing may generate multiple isoforms.
• It belongs to the Krueppel C2H2-type zinc-finger protein family, which features DNA-binding zinc finger motifs.
• The protein is predicted to participate in transcriptional regulation, likely through sequence-specific DNA binding at gene regulatory regions.
• ZNF587 localizes to the nucleus, consistent with its putative role in controlling gene expression.
• It contains multiple C2H2 zinc finger domains that coordinate zinc ions, essential for DNA binding and transcriptional activity.
• The protein has been detected in mass spectrometry-based proteomics analyses, indicating its expression across various human tissues.

Experimental Guidance and Technical Tips

• For Western blot (WB), the antibody detects a band at approximately 66 kDa; consider loading whole-cell lysates of human, mouse, or rat origin and using appropriate positive controls.
• Since the antibody is a polyclonal, titrate the working dilution for each application and validate specificity in your sample system; batch-to-batch variability may occur.
• For ELISA, use the recombinant immunogen (amino acids 120–240) as a coating standard to assess antibody binding; consider checkerboard titrations for optimal conditions.
• The immunogen corresponds to a region between predicted zinc finger domains; the antibody may recognize multiple ZNF587 isoforms if the epitope is conserved; confirm reactivity in your specific cellular context.

CamelBio: Your One-Stop Sourcing Bridge

CamelBio supports diagnostic manufacturers and research labs with a comprehensive portfolio of IVD raw materials, including validated polyclonal antibodies like this anti-ZNF587 reagent. Our offerings cover rare target sourcing, bulk ancillary reagents, and optimized antibody pairs, streamlining your transition from discovery to clinical application.