Anti-ZNF563 Polyclonal Antibody for WB and ELISA - Q8TA94

Core Product Specifications and Parameters

Biological Background: ZNF563 Function and Localization

• Zinc finger protein 563 (ZNF563) is a member of the zinc finger family, characterized by the presence of multiple C2H2-type zinc finger domains that mediate DNA binding.
• It is predicted to function as a transcription factor, likely involved in the regulation of gene expression.
• The protein localizes to the nucleus, consistent with its role in transcriptional regulation.
• Alternative splicing of the ZNF563 gene produces multiple transcript variants, potentially encoding distinct protein isoforms.
• As a metal-binding protein, ZNF563 requires zinc ions for structural integrity and DNA-binding activity.
• ZNF563 is included in the UniProt reference proteome, representing the canonical human proteome.

Experimental Guidance and Technical Tips

• The immunogen is a synthetic peptide derived from the N-terminal region (amino acids 1-100) of human ZNF563. The resulting polyclonal antibody may recognize multiple isoforms if the N-terminus is conserved.
• For Western blot, a band around 55 kDa (predicted molecular weight 55.4 kDa) is expected. Consider using appropriate controls to confirm specificity.
• This antibody has been reported to cross-react with mouse and rat ZNF563, likely due to sequence homology. Validation in the relevant sample system is recommended.
• For ELISA, optimization of coating antigen and antibody concentration may be required based on the specific assay format.

CamelBio: Your One-Stop Sourcing Bridge

CamelBio supports diagnostic manufacturers, laboratories, and research institutes with comprehensive access to IVD raw materials. For projects requiring antibodies targeting transcriptional regulators like ZNF563, we offer validated polyclonal antibodies, matched antibody pairs, and bulk ancillary reagents. Our sourcing network also assists in obtaining rare-target raw materials, ensuring a reliable supply chain from concept to clinic.