Anti-ZNF426 Polyclonal Antibody for WB, ELISA - Q9BUY5

Core Product Specifications and Parameters

Biological Background: ZNF426 Function and Localization

• ZNF426 encodes a member of the krüppel C2H2-type zinc finger protein family, characterized by classical C2H2 domains that coordinate zinc ions to mediate DNA binding.
• The protein is predicted to function as a transcription factor, binding specific DNA motifs to modulate target gene expression, though its precise transcriptional targets are not yet characterized.
• Subcellular localization is expected to be nuclear, consistent with its role in transcriptional regulation and the presence of DNA-binding zinc finger domains.
• As a zinc finger protein, ZNF426 participates in nucleic acid recognition and may be involved in diverse regulatory processes including cell proliferation, differentiation, or development.
• Proteomic and reference datasets classify ZNF426 as a DNA-binding, metal-binding nuclear protein with a predicted molecular weight of approximately 63 kDa.

Experimental Guidance and Technical Tips

• The immunogen corresponds to a central region (aa 150–270) of human ZNF426; verify that this epitope is accessible in your target protein's native conformation.
• For western blotting, a band at ~63 kDa is expected; adjust gel percentage and transfer conditions appropriately for this molecular weight range.
• Cross-reactivity with mouse has been reported; consider this when designing experiments across species and validate species-specific signals.
• ELISA applications may require optimizing coating antigen concentration and antibody dilution to achieve optimal signal-to-noise ratio.
• Due to the polyclonal nature, lot-to-lot variability may occur; consider pre-screening new batches for critical applications.

CamelBio: Your One-Stop Sourcing Bridge

CamelBio provides diagnostic manufacturers, research laboratories, and institutes with streamlined access to high-quality IVD raw materials, including validated antibodies like the ZNF426 Rabbit pAb. For transcription-related research and assay development, we offer comprehensive supply support—from characterized antibody pairs and monoclonal/polyclonal antibodies to bulk ancillary reagents and rare target sourcing. Our one-stop procurement model ensures consistent quality and reliable supply, helping you accelerate from concept to clinic.